Having received the feedback of midterm presentation, our group discussed several times about our topic. Finally, we changed our idea from bio-monitor into the bio-information. For bio-information, the first inspiration is that exchanging information in bacteria.
Bacteria do not have an obligate sexual reproductive stage in their life cycle, but they can be very active in the exchange of genetic information. The genetic information carried in the DNA can be transferred from one cell to another. There is an article said two CRISPR-mediated analogue multi-event recording apparatus (CAMERA) systems that use base editors and Cas9 nucleases to record cellular events in bacteria and mammalian cells. Therefore, we came up with the idea that using bacteria to store different kinds of information in different kinds of bacteria. We have used physical ways to store our information like the name card, bank card, and so on. We could store these kinds of information into bacteria. Also, we could classify the information in the different level that to ensure the safety of information. Here is some scenario I draw to express.
Firstly, shaking hands with someone who we need to meet. We could exchange our information like personal information. Shaking hands is the processing to exchange information. We could store our personal information into our hands first so that we could use it to exchange and analyze it on our computer.
The second one is to make our card’s information into bacteria such as student’s card, bank card or identification. In this way, we could avoid the information leakage when we use our bacteria to transfer our information and disappear immediately.
The last one is targeting our information by using bacteria. We usually have not classified our information in different levels, therefore, we could target our information and decide what kind of information need to protect and what kind of is not important as others.
Last but not least, there is a way to nanopore DNA sequencer, the MinION. The MinION is a portable, real-time, long-read, low-cost device for DNA and RNA sequencing. In that way, we could analyze the DNA in bacteria and receive the information from that.
1.Encyclopedia Britannica. (2018). bacteria | Cell, Evolution, & Classification – Exchange of genetic information. [online] Available at: https://www.britannica.com/science/bacteria/Exchange-of-genetic-information [Accessed 25 Mar. 2018].
2.Tang, W. and Liu, D. (2018). Rewritable multi-event analog recording in bacterial and mammalian cells. Science, p.eaap8992.
3.https://nanoporetech.com/products/minionPortable, real-time biological analyses